RUSH TRANSCRIPT As the ░░░░░░░░ fights to curb the ░░░░░░░░ of this pandemic the ░░░░░░░░ word is working on ░░░░░░░░ short term fix that ░░░░░░░░ treat more than 34 ░░░░░░░░ people across the country ░░░░░░░░ have already tested positive ░░░░░░░░ the Coronavirus And they ░░░░░░░░ be getting closer Last ░░░░░░░░ a team of researchers ░░░░░░░░ a report that detailed ░░░░░░░░ 70 drugs that already ░░░░░░░░ and might be effective ░░░░░░░░ treating the Coronavirus Meanwhile ░░░░░░░░ president is pushing an ░░░░░░░░ Coronavirus drug and patients ░░░░░░░░ probably don t need ░░░░░░░░ yet are stocking up ░░░░░░░░ me to discuss Dr ░░░░░░░░ Hazeltine infectious disease expert ░░░░░░░░ president of access health ░░░░░░░░ Doctor thank you for ░░░░░░░░ me this morning This ░░░░░░░░ says it may be ░░░░░░░░ to repurpose existing treatments ░░░░░░░░ than create a new ░░░░░░░░ from scratch Do these ░░░░░░░░ treatments actually work The ░░░░░░░░ treatments aren t known ░░░░░░░░ work yet That certainly ░░░░░░░░ be the quickest way ░░░░░░░░ do it but they ░░░░░░░░ to be tested There ░░░░░░░░ more than 25 drugs ░░░░░░░░ already are approved that ░░░░░░░░ to 70 that you ░░░░░░░░ for other indications They ░░░░░░░░ be effective In addition ░░░░░░░░ that there are a ░░░░░░░░ of other drugs that ░░░░░░░░ against the virus directly ░░░░░░░░ chemicals drug candidates that ░░░░░░░░ against the virus directly ░░░░░░░░ are already known to ░░░░░░░░ the virus but haven ░░░░░░░░ been fully tested in ░░░░░░░░ trials yet You ve ░░░░░░░░ to test these drugs ░░░░░░░░ humans against the virus ░░░░░░░░ you know what the ░░░░░░░░ will be Then how ░░░░░░░░ do those clinical trials ░░░░░░░░ Let s We can ░░░░░░░░ those very dramatically We ░░░░░░░░ accelerate them so that ░░░░░░░░ if you have a ░░░░░░░░ that s approved you ░░░░░░░░ test it in somebody ░░░░░░░░ is infected and you ░░░░░░░░ see very quickly by ░░░░░░░░ s called a surrogate ░░░░░░░░ That is just watching ░░░░░░░░ level of virus in ░░░░░░░░ blood drop That s ░░░░░░░░ marker that the drug ░░░░░░░░ going to work If ░░░░░░░░ see that working You ░░░░░░░░ t even have to ░░░░░░░░ for them to get ░░░░░░░░ You know that the ░░░░░░░░ the drug is working ░░░░░░░░ you can begin to ░░░░░░░░ its use dramatically It ░░░░░░░░ take once you test ░░░░░░░░ in people it can ░░░░░░░░ a very short time ░░░░░░░░ would say a matter ░░░░░░░░ one or two weeks ░░░░░░░░ the most if the ░░░░░░░░ is already approved If ░░░░░░░░ isn t approved then ░░░░░░░░ needs testing I think ░░░░░░░░ will say probably until ░░░░░░░░ summer But I m ░░░░░░░░ optimistic that we re ░░░░░░░░ to be able to ░░░░░░░░ this virus with drugs ░░░░░░░░ not only to treat ░░░░░░░░ people but an idea ░░░░░░░░ I don t think ░░░░░░░░ people think about using ░░░░░░░░ to prevent infection in ░░░░░░░░ first place That s ░░░░░░░░ we do with Malaria ░░░░░░░░ take drugs if you ░░░░░░░░ going into Malaria zone ░░░░░░░░ drugs that work against ░░░░░░░░ virus can used for ░░░░░░░░ purposes Treating those who ░░░░░░░░ sick and preventing those ░░░░░░░░ are exposed from being ░░░░░░░░ So you agree with ░░░░░░░░ president that using these ░░░░░░░░ Malaria drugs to treat ░░░░░░░░ could be a somewhat ░░░░░░░░ a golden ticket I ░░░░░░░░ t necessarily agree with ░░░░░░░░ Malaria drugs That remains ░░░░░░░░ be seen But I ░░░░░░░░ agree that there are ░░░░░░░░ number of chemicals that ░░░░░░░░ in clinical trials Some ░░░░░░░░ them have been approved ░░░░░░░░ human use which must ░░░░░░░░ tested in humans infected ░░░░░░░░ the virus before we ░░░░░░░░ Malaria may be premature ░░░░░░░░ don t know the ░░░░░░░░ to the anti malarial ░░░░░░░░ We don t know ░░░░░░░░ But the concept I ░░░░░░░░ trying to get at ░░░░░░░░ using the drugs to ░░░░░░░░ infection as well as ░░░░░░░░ treat infection And that ░░░░░░░░ the context in which ░░░░░░░░ raise Malaria The president ░░░░░░░░ mentioned several drugs out ░░░░░░░░ and what has happened ░░░░░░░░ have gone out and ░░░░░░░░ up on them and ░░░░░░░░ people who currently need ░░░░░░░░ drugs like people with ░░░░░░░░ diseases like lupus can ░░░░░░░░ get them How big ░░░░░░░░ a risk is it ░░░░░░░░ we talk about these ░░░░░░░░ that it can do ░░░░░░░░ harm than good that ░░░░░░░░ who need them they ░░░░░░░░ no longer available It ░░░░░░░░ do some harm because ░░░░░░░░ who need the drugs ░░░░░░░░ the drugs And these ░░░░░░░░ yet as unproven in ░░░░░░░░ trials All of us ░░░░░░░░ think who study these ░░░░░░░░ are optimistic that we ░░░░░░░░ have these drugs Probably ░░░░░░░░ quickest way to stop ░░░░░░░░ epidemic other than very ░░░░░░░░ quarantine measures is to ░░░░░░░░ these drugs tested And ░░░░░░░░ are ways to accelerate ░░░░░░░░ drugs When drugs when ░░░░░░░░ were threatened with an ░░░░░░░░ attack I was able ░░░░░░░░ develop a drug rather ░░░░░░░░ that was stockpiled by ░░░░░░░░ U S Government We ░░░░░░░░ how to do it ░░░░░░░░ thing we re really ░░░░░░░░ at is doing this ░░░░░░░░ we can accelerate the ░░░░░░░░ We ve gone through ░░░░░░░░ whole routine with HIV ░░░░░░░░ We have put in ░░░░░░░░ all the mechanisms we ░░░░░░░░ for rapid approval for ░░░░░░░░ testing and surrogate measures ░░░░░░░░ knowing whether or not ░░░░░░░░ drugs work But until ░░░░░░░░ have that data that ░░░░░░░░ data from controlled human ░░░░░░░░ we won t know ░░░░░░░░ ones to use And ░░░░░░░░ there s no point ░░░░░░░░ going out and stockpiling ░░░░░░░░ of these drugs until ░░░░░░░░ trying to get these ░░░░░░░░ until we know which ░░░░░░░░ work or not Doctor ░░░░░░░░ you so much I ░░░░░░░░ you joining us Definitely ░░░░░░░░ us a bit smarter ░░░░░░░░ a really important subject.