RUSH TRANSCRIPT About cosentyx ░░░░░░░░ parents are struggling to ░░░░░░░░ their hands on amoxicillin ░░░░░░░░ a nation white shortage ░░░░░░░░ Hu is in New ░░░░░░░░ with the latest reporter ░░░░░░░░ cvs just mind me ░░░░░░░░ very low on amoxicillin ░░░░░░░░ s a popular antibiotic ░░░░░░░░ to treat many children ░░░░░░░░ it s happening as ░░░░░░░░ country is grappling on ░░░░░░░░ shortage of antibiotics and ░░░░░░░░ It s because many ░░░░░░░░ the ingredients that are ░░░░░░░░ to make medications for ░░░░░░░░ country are coming from ░░░░░░░░ and in fact 83 ░░░░░░░░ the companies responsible for ░░░░░░░░ ingredients are foreign That ░░░░░░░░ according to the U ░░░░░░░░ a non profit And ░░░░░░░░ you take a look ░░░░░░░░ you can see how ░░░░░░░░ like China and India ░░░░░░░░ grown their supply of ░░░░░░░░ ingredients to the United ░░░░░░░░ companies in India the ░░░░░░░░ here you see shaded ░░░░░░░░ green they were associated ░░░░░░░░ 20 of the ingredients ░░░░░░░░ in 2000 but by ░░░░░░░░ end of last year ░░░░░░░░ had grown to 62 ░░░░░░░░ the year China the ░░░░░░░░ in blue grew from ░░░░░░░░ to 23 while the ░░░░░░░░ of American companies making ░░░░░░░░ ingredients the part here ░░░░░░░░ red well that shrank ░░░░░░░░ 15 to just 4 ░░░░░░░░ talked with the CEO ░░░░░░░░ U S Antibiotics which ░░░░░░░░ itself as the only ░░░░░░░░ U S Manufacturer of ░░░░░░░░ brand products and other ░░░░░░░░ allow companies to produce ░░░░░░░░ and their ingredients at ░░░░░░░░ low cost which is ░░░░░░░░ American companies out in ░░░░░░░░ race to the bottom ░░░░░░░░ prices Just in the ░░░░░░░░ of amoxicillin the Chinese ░░░░░░░░ made a very conscience ░░░░░░░░ to invest heavily in ░░░░░░░░ very large production facilities ░░░░░░░░ China so they drove ░░░░░░░░ lot of companies that ░░░░░░░░ in the United States ░░░░░░░░ amoxicillin and those companies ░░░░░░░░ out of business For ░░░░░░░░ number of reasons but ░░░░░░░░ think primarily it was ░░░░░░░░ the price dropping so ░░░░░░░░ reporter U S antibiotics ░░░░░░░░ in touch with the ░░░░░░░░ about boosting supply of ░░░░░░░░ but the CEO says ░░░░░░░░ needs to be done ░░░░░░░░ bring the supply chain ░░░░░░░░ manufacturing back to the ░░░░░░░░ States He says until ░░░░░░░░ happens pharmacies like this ░░░░░░░░ will continue to experience ░░░░░░░░ moving into the future ░░░░░░░░ to you Jackie Lydia ░░░░░░░░ thank you so much ░░░░░░░░ me now nyu school ░░░░░░░░ medicine clinical associate professor ░░░░░░░░ Devi It s good ░░░░░░░░ see you and we ░░░░░░░░ not even in the ░░░░░░░░ of the season yet ░░░░░░░░ it comes to Covid ░░░░░░░░ rsv and flu Give ░░░░░░░░ your perspective on how ░░░░░░░░ this season will be ░░░░░░░░ will we be accurately ░░░░░░░░ given the shortage that ░░░░░░░░ just described Well the ░░░░░░░░ here is is that ░░░░░░░░ viral illnesses predispose you ░░░░░░░░ get bacterial complications so ░░░░░░░░ s where you need ░░░░░░░░ antibiotics You can have ░░░░░░░░ that can spread to ░░░░░░░░ blood so there is ░░░░░░░░ obvious issue if you ░░░░░░░░ a bacterial infection and ░░░░░░░░ s untreated then you ░░░░░░░░ develop a complication and ░░░░░░░░ s a longer time ░░░░░░░░ that you go and ░░░░░░░░ sick but then there ░░░░░░░░ also an issue that ░░░░░░░░ re wasting time that ░░░░░░░░ top of that you ░░░░░░░░ be calling doctor s ░░░░░░░░ you might be going ░░░░░░░░ to pharmacy in search ░░░░░░░░ treatment so the doctor ░░░░░░░░ office may already be ░░░░░░░░ with sick patients and ░░░░░░░░ they are trying to ░░░░░░░░ with this trying to ░░░░░░░░ out oh could it ░░░░░░░░ be that that pharmacy ░░░░░░░░ short Maybe I should ░░░░░░░░ a prescription some place ░░░░░░░░ so that makes it ░░░░░░░░ so that if the ░░░░░░░░ office has limited resources ░░░░░░░░ while they are spending ░░░░░░░░ on this they aren ░░░░░░░░ treating other patients Meanwhile ░░░░░░░░ pharmacy also is getting ░░░░░░░░ with this and also ░░░░░░░░ you travel place to ░░░░░░░░ you maybe spreading infections ░░░░░░░░ in the meantime right ░░░░░░░░ great point So that ░░░░░░░░ the short term ripple ░░░░░░░░ Then on top of ░░░░░░░░ we think about the ░░░░░░░░ term issues so if ░░░░░░░░ realize okay well amoxicillin ░░░░░░░░ in shortage at multiple ░░░░░░░░ we can t do ░░░░░░░░ then people s reaction ░░░░░░░░ be well let s ░░░░░░░░ to a stronger drug ░░░░░░░░ we don t want ░░░░░░░░ deal with this shortage ░░░░░░░░ we don t want ░░░░░░░░ perp to develop complications ░░░░░░░░ then in the long ░░░░░░░░ you have a problem ░░░░░░░░ antibiotic resistance that you ░░░░░░░░ using stronger drugs to ░░░░░░░░ this infection and so ░░░░░░░░ the long term jackie ░░░░░░░░ mother would always explain ░░░░░░░░ to me that really ░░░░░░░░ only want to take ░░░░░░░░ when you need them ░░░░░░░░ you re talking about ░░░░░░░░ stronger one to treat ░░░░░░░░ more minor then if ░░░░░░░░ need the stronger one ░░░░░░░░ s going to be ░░░░░░░░ effective basically Exactly Exactly ░░░░░░░░ okay moving on from ░░░░░░░░ for right now because ░░░░░░░░ was an article that ░░░░░░░░ a hot topic amongst ░░░░░░░░ conversation I was having ░░░░░░░░ s a new Moderna ░░░░░░░░ vaccine showing breakthrough results ░░░░░░░░ I wanted to ask ░░░░░░░░ about this because a ░░░░░░░░ of people are very ░░░░░░░░ Yeah so this is ░░░░░░░░ very promising I thought ░░░░░░░░ was very exciting but ░░░░░░░░ is the idea There ░░░░░░░░ a study that came ░░░░░░░░ about a cancer vaccine ░░░░░░░░ is for melanoma patients ░░░░░░░░ showed potentially this new ░░░░░░░░ vaccine it s not ░░░░░░░░ on the market yet ░░░░░░░░ that it could improve ░░░░░░░░ or at least recurrence ░░░░░░░░ these patients that have ░░░░░░░░ Now with these studies ░░░░░░░░ s always tricky like ░░░░░░░░ do you know if ░░░░░░░░ study is any good ░░░░░░░░ what but essentially they ░░░░░░░░ at these patients a ░░░░░░░░ over 150 patients who ░░░░░░░░ melanoma treated surgically but ░░░░░░░░ are advanced so it ░░░░░░░░ stage three and four ░░░░░░░░ they were looking to ░░░░░░░░ if they could delay ░░░░░░░░ recurrence and they watched ░░░░░░░░ for about a year ░░░░░░░░ then a random group ░░░░░░░░ these patients received the ░░░░░░░░ vaccine so this is ░░░░░░░░ top of keytruda which ░░░░░░░░ all got which is ░░░░░░░░ treatment so basically looking ░░░░░░░░ this incremental effect of ░░░░░░░░ cancer vaccine Jackie wow ░░░░░░░░ it delayed yeah it ░░░░░░░░ the recurrence or decreased ░░░░░░░░ chance of death by ░░░░░░░░ which is a tremendous ░░░░░░░░ Jackie that is That ░░░░░░░░ extraordinary Yeah Jackie dr ░░░░░░░░ We re out of ░░░░░░░░ Thank you so much ░░░░░░░░ breaking that down for ░░░░░░░░ and of course we ░░░░░░░░ have you back on ░░░░░░░░ soon So many issues ░░░░░░░░ like to discuss with ░░░░░░░░ to get your perspective ░░░░░░░░ you.